Article
TFIIA plays a role in the response to oxidative stress.
Eukaryotic cell - 1 Jul 2006
Kraemer Susan M, Goldstrohm David A, Berger Ann, Hankey Susan, Rovinsky Sherry A, Scott Moye-Rowley W, Stargell Laurie A
Abstract excerpt
To characterize the role of the general transcription factor TFIIA in the regulation of gene expression by RNA polymerase II, we examined the transcriptional profiles of TFIIA mutants of Saccharomyces cerevisiae using DNA microarrays. Whole-genome expression profiles were determined for three different mutants with mutations in the gene coding for the small subunit of TFIIA, TOA2. Depending on the particular...
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