Article
In vivo regulation of low-density lipoprotein receptor and apolipoprotein B gene expressions by dietary fat and cholesterol in inbred strains of mice.
Biochimica et biophysica acta - 15 Oct 1991
Srivastava R A, Jiao S, Tang J J, Pfleger B A, Kitchens R T, Schonfeld G
Abstract excerpt
Two proteins that may be important in the hypercholesterolemia and atherosclerosis produced by dietary fat and/or cholesterol are apoB and the LDL-receptor. We evaluated the molecular and genetic regulation of these two proteins by two important components of atherogenic diets: dietary fatty acids and dietary cholesterol. The control diet (C) contained 5% corn oil; the high cholesterol (HC) diets, 5% corn oil...
Topics
- Alleles
- Animals
- Apolipoproteins B
- Cholesterol, Dietary
- Dietary Fats
- Female
- Gene Expression Regulation
- Intestinal Mucosa
- Liver
- Mice
- Mice, Inbred Strains