Article
Polymorphism of Toll-like receptor 9 (TLR9) gene in sheep.
Veterinary immunology and immunopathology - 15 Jan 2008
Zhou Huitong, Hickford Jon G H
Abstract excerpt
Bacterial and synthetic DNA containing unmethylated CpG dinucleotides in particular sequence contexts, activates the vertebrate immune system through Toll-like receptor 9 (TLR9). In this study, we use PCR-single-strand conformational polymorphism (PCR-SSCP) analysis to investigate genetic variation in a key region of the ovine TLR9 gene. Three novel SSCP patterns, representing three different sequences, were...
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