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Article

TEL/ETV6 induces apoptosis in 32D cells through p53-dependent pathways.

Biochemical and biophysical research communications - 25 Aug 2006

Yamagata Tetsuya, Maki Kazuhiro, Waga Kazuo, Mitani Kinuko

Abstract excerpt

TEL is an ETS family transcription factor that is critical for maintaining hematopoietic stem cells in adult bone marrow. To investigate the roles of TEL in myeloid proliferation and differentiation, we introduced TEL cDNA into mouse myeloid 32Dcl3 cells. Overexpression of TEL repressed interleukin-3-dependent proliferation through blocking cell cycle progression. Also, the presence of TEL triggered apoptosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16828711
DOI: 10.1016/j.bbrc.2006.06.127

Genes

ETV6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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