Article
PEX16 contributes to peroxisome maintenance by constantly trafficking PEX3 via the ER.
Journal of cell science - 1 Sept 2014
Aranovich Alexander, Hua Rong, Rutenberg Andrew D, Kim Peter K
Abstract excerpt
The endoplasmic reticulum (ER) is required for the de novo biogenesis of peroxisomes in mammalian cells. However, its role in peroxisome maintenance is unclear. To explore ER involvement in the maintenance of peroxisomes, we redirect a peroxisomal membrane protein (PMP), PEX3, to directly target...
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