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Article

Multidrug-resistant phenotype in retinoblastoma correlates with P-glycoprotein expression.

Ophthalmology - 1 Sept 1991

Chan H S, Thorner P S, Haddad G, Gallie B L

Abstract excerpt

Chemotherapy plays an important role in therapy for patients with extraocular and metastatic retinoblastoma. The authors used chemotherapy for management of selected patients with uncontrolled intraocular tumors or tumors larger and more posteriorly located than those conventionally treated with local cryotherapy or photocoagulation. Rapid regrowth of some tumors after an initial excellent chemotherapy response...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Antineoplastic Combined Chemotherapy Protocols
Blood Proteins
Carrier Proteins
Drug Resistance
Eye Neoplasms
Humans
Immunoenzyme Techniques
Membrane Glycoproteins
Neoplasm Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Retinoblastoma

Tumor Cells, Cultured

Source

Identifiers

PMID: 1682862
DOI: 10.1016/s0161-6420(91)32134-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1682862-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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