Article
Analysis of DNA mismatch repair gene expression and mutations in thyroid tumours.
Anticancer research - 1 Jan 2000
Ruschenburg Ilka, Vollheim Beate, Stachura Jerzy, Cordon-Cardo Carlos, Korabiowska Monika
Abstract excerpt
Alterations of DNA mismatch repair genes, primarily demonstrated in hereditary nonpolyposis colorectal carcinomas, were reported to be of relevance for the progression of several sporadic tumours. In this study, the expression and mutations of MLH1, MSH2, PMS1 and PMS2 in a panel of thyroid tumours, including nodular hyperplasia, follicular adenomas and carcinomas, were investigated. The expressions of MLH1, MSH2...
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