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Article

Primary breast cancer phenotypes associated with propensity for central nervous system metastases.

Cancer - 15 Aug 2006

Tham Yee-Lu, Sexton Krystal, Kramer Rita, Hilsenbeck Susan, Elledge Richard

Abstract excerpt

BACKGROUND: There is anecdotal evidence that the incidence of central nervous system (CNS) metastases in breast cancer patients is increasing. It is unclear whether specific tumor biological properties or the use of systemic therapies influence this risk. METHODS: Using a database of 10,782 patients, 2685 patients were identified who experienced recurrence distantly. Clinical and biological features were analyzed...

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Share to Carcinoma, Ductal, Breast
Share to Carcinoma, Intraductal, Noninfiltrating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Recurrence, Local

Share to Receptor, ErbB-2

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Source

Identifiers

PMID: 16826579
DOI: 10.1002/cncr.22041

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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