Article
Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse.
Breast cancer research and treatment - 1 Apr 2012
Harrell J Chuck, Prat Aleix, Parker Joel S, Fan Cheng, He Xiaping, Carey Lisa, Anders Carey, Ewend Matthew, Perou Charles M
Abstract excerpt
The ability to predict metastatic potential could be of great clinical importance, however, it is uncertain if predicting metastasis to specific vital organs is feasible. As a first step in evaluating metastatic predictions, we analyzed multiple primary tumors and metastasis pairs and determined that >90% of 298 gene expression signatures were found to be similarly expressed between matched pairs of tumors and...
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