Article
Estradiol increases platelet aggregation in Pl(A1/A1) individuals.
American heart journal - 1 Jul 2006
Boudoulas Konstantinos D, Montague Christine Roos, Goldschmidt-Clermont Pascal J, Cooke Glen E
Abstract excerpt
BACKGROUND: The platelet glycoprotein IIb/IIIa receptor is a key mediator of platelet aggregation and intracoronary thrombosis. Studies have suggested that hormone replacement therapy (HRT) may increase coronary events in postmenopausal women. OBJECTIVES: We sought to characterize the relationship between the estrogen concentration expected in HRT and platelet aggregation. DESIGN AND RESULTS: Platelet aggregation...
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