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Article

Identification of a regulatory autophosphorylation site in the serine-threonine kinase RIP2.

Cellular signalling - 1 Dec 2006

Dorsch Marion, Wang Anlai, Cheng Hong, Lu Chafen, Bielecki Andrew, Charron Kathryn, Clauser Karl, Ren Hong, Polakiewicz Roberto D, Parsons Tom, Li Ping, Ocain Tim, Xu Yajun

Abstract excerpt

Receptor-interacting protein 2 (RIP2) is a serine-threonine kinase that mediates signaling for many receptors of the innate and adaptive immune systems. Toll like receptors (TLR) are an important component of the innate immune response. Stimulation of RIP2-deficient cells with ligands for TLR 2, 3 and 4 results in impaired cytokine production and decreased activation of NF-kB and MAP kinases compared to wild-type...

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Identifiers

PMID: 16824733
DOI: 10.1016/j.cellsig.2006.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Identification of a regulatory autophosphorylation site in the serine-threonine kinase RIP2.PMID 16824733Read ↗

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