Article
A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy.
Archives of general psychiatry - 1 Jan 2006
Brookes Keeley-Joanne, Mill Jon, Guindalini Camilla, Curran Sarah, Xu Xiaohui, Knight Jo, Chen Chih-Ken, Huang Yu-Shu, Sethna Vaheshta, Taylor Eric, Chen Wai, Breen Gerome, Asherson Philip
Abstract excerpt
CONTEXT: Attention-deficit/hyperactivity disorder (ADHD) is a common heritable childhood behavioral disorder. Identifying risk factors for ADHD may lead to improved intervention and prevention. The dopamine transporter gene (DAT1) is associated with ADHD in several studies, with an average 1.2 odds ratio and evidence of heterogeneity across data sets. OBJECTIVE: To investigate sources of heterogeneity by refining...
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