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Article

Depression of biofilm formation and antibiotic resistance by sarA disruption in Staphylococcus epidermidis.

World journal of gastroenterology - 7 Jul 2006

Tao Ju-Hong, Fan Chang-Sheng, Gao Shan-E, Wang Hai-Jiao, Liang Guo-Xin, Zhang Qing

Abstract excerpt

AIM: To study the effects of disruption of sarA gene on biofilm formation and antibiotic resistance of Staphylococcus epidermidis (S. epidermidis). METHODS: In order to disrupt sarA gene, the double-crossover homologous recombination was applied in S. epidermidis RP62A, and tetracycline resistance gene (tet) was used as the selective marker which was amplified by PCR from the pBR322 and inserted into the locus...

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Identifiers

PMID: 16810749
DOI: 10.3748/wjg.v12.i25.4009
PMCID: PMC4087711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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