Article
Haplotype of signal transducer and activator of transcription 3 gene predicts cardiovascular disease in dialysis patients.
Journal of the American Society of Nephrology : JASN - 1 Aug 2006
Zhang Lin, Kao W H Linda, Berthier-Schaad Yvette, Liu Yongmei, Plantinga Laura, Jaar Bernard G, Fink Nancy, Powe Neil, Klag Michael J, Smith Michael W, Coresh Josef
Abstract excerpt
Signal transducer and activator of transcription 3 (STAT3) protein has been linked to cardiovascular disease (CVD) through multiple pathways in experimental and animal studies. STAT3 gene variation was examined as a predictor of incident CVD in a subcohort of 529 incident white dialysis patients. Fifteen single-nucleotide polymorphisms of the STAT3 gene were genotyped. Haplotypes were estimated using software...
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