Article
Interleukin 6 (rs1800795) and pentraxin 3 (rs2305619) polymorphisms-association with inflammation and all-cause mortality in end-stage-renal disease patients on dialysis.
Scientific reports - 20 Jul 2021
Rocha Susana, Valente Maria João, Coimbra Susana, Catarino Cristina, Rocha-Pereira Petronila, Oliveira José Gerardo, Madureira José, Fernandes João Carlos, do Sameiro-Faria Maria, Miranda Vasco, Belo Luís, Santos-Silva Alice, Bronze-da-Rocha Elsa
Abstract excerpt
Chronic inflammation plays an important role in the progression and outcome of chronic kidney disease (CKD). The circulating levels of the inflammatory biomarkers interleukin 6 (IL6) and pentraxin 3 (PTX3) are enhanced in CKD patients, and are associated with the progression of the disease and with higher risk for cardiovascular events, the major cause of death in CKD patients. Our aim was to study how specific...
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