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Article

Association of single-nucleotide polymorphisms in JAK3, STAT4, and STAT6 with new cardiovascular events in incident dialysis patients.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 May 2009

Sperati C John, Parekh Rulan S, Berthier-Schaad Yvette, Jaar Bernard G, Plantinga Laura, Fink Nancy, Powe Neil R, Smith Michael W, Coresh Josef, Kao W H Linda

Abstract excerpt

BACKGROUND: Increasing evidence supports a role for cell-mediated immunity in the pathogenesis of cardiovascular disease. Single-nucleotide polymorphisms (SNPs) in JAK3, STAT4, and STAT6 of the Janus kinase-signal transducer and activator of transcription (Jak-Stat) signal transduction pathway were examined for association with time to new cardiovascular events in incident dialysis patients from the Choices for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19282076
DOI: 10.1053/j.ajkd.2008.12.025
PMCID: PMC2744364

Genes

JAK3
STAT4
STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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