Article
Angiotensin-related genetic determinants of cardiovascular disease in patients undergoing hemodialysis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Nov 2019
Moe Sharon M, Long Jin, Schwantes-An Tae-Hwi Linus, Decker Brian S, Wetherill Leah, Edenberg Howard J, Xuei Xiaoling, Vatta Matteo, Foroud Tatiana M, Chertow Glenn M
Abstract excerpt
BACKGROUND: Cardiovascular mortality in patients receiving dialysis remains unacceptably high, with unexplained ancestry differences suggesting a genetic component. METHODS: We analyzed DNA samples from 37% of subjects enrolled in the EValuation Of Cinacalcet Hydrochloride (HCl) Therapy to Lower CardioVascular Events (EVOLVE) trial, a randomized trial conducted in patients receiving hemodialysis with secondary...
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