Article
Potential regulatory SNPs in promoters of human genes: a systematic approach.
Molecular and cellular probes - 1 Dec 2006
Stepanova Maria, Tiazhelova Tatiana, Skoblov Mikle, Baranova Ancha
Abstract excerpt
Single nucleotide polymorphisms (SNPs) can significantly contribute to the cellular level of the mRNA transcripts encoded by human disease related genes. DNA variations between individuals can be an indication of predisposition to disease or affect the response to treatment. An algorithm allowing in silico extraction of SNPs with the high probability of influencing the level of gene expression is highly...
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