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Detection and characterization of DNA variants in the promoter regions of hundreds of human disease candidate genes.

Genomics - 1 Jun 2006

Sinnett Daniel, Beaulieu Patrick, Bélanger Hélène, Lefebvre Jean-François, Langlois Sylvie, Théberge Marie-Christine, Drouin Simon, Zotti Corinne, Hudson Thomas J, Labuda Damian

Abstract excerpt

Understanding genetic variation might reveal the cause of individual susceptibility to a variety of complex diseases such as asthma, diabetes, and cancer. Current efforts to identify functional DNA variants have essentially been oriented toward single nucleotide polymorphisms (SNPs) found in coding regions of candidate genes since they have direct impact on the structure and function of the affected proteins....

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PMID: 16500075
DOI: 10.1016/j.ygeno.2006.01.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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