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Article

Sustained virological response to peginterferon plus ribavirin in chronic hepatitis C genotype 1 patients is associated with a persistent Th1 immune response.

Alimentary pharmacology & therapeutics - 1 Jul 2006

Trapero-Marugán M, García-Buey L, Muñoz C, Quintana N E, Moreno-Monteagudo J A, Borque M J, Fernández M J, Salvanés F R, Medina J, Moreno-Otero R

Abstract excerpt

BACKGROUND: An impairment of cellular immune response may contribute to the persistency of hepatitis C virus infection. AIM: To analyse the Th1/Th2 cytokine profile in peripheral blood CD4(+) and CD8(+) T cells from patients with chronic hepatitis C (CHC) during treatment with pegylated interferon-alpha2a plus ribavirin and to correlate the Th1/Th2 balance with virological response (SVR). METHODS: Prospective...

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Identifiers

PMID: 16803610
DOI: 10.1111/j.1365-2036.2006.02954.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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