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Article

Abnormal differentiation of memory T cells in systemic lupus erythematosus.

Arthritis and rheumatism - 1 Jul 2006

Fritsch Ruth D, Shen Xinglei, Illei Gabor G, Yarboro Cheryl H, Prussin Calman, Hathcock Karen S, Hodes Richard J, Lipsky Peter E

Abstract excerpt

OBJECTIVE: The chemokine receptor CCR7 and the tumor necrosis factor receptor family member CD27 define 3 distinct, progressively more differentiated maturational stages of CD4 memory subpopulations in healthy individuals: the CCR7+, CD27+, the CCR7-, CD27+, and the CCR7-, CD27- populations. The goal of this study was to examine maturational disturbances in CD4 T cell differentiation in systemic lupus...

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Share to CD4-Positive T-Lymphocytes
Share to Immunologic Memory

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lupus Erythematosus, Systemic

Share to Receptors, CCR7

Share to Receptors, Chemokine

Share to Receptors, CXCR4

Share to Telomerase

Share to Tumor Necrosis Factor Receptor Superfamily, Member 7

Source

Identifiers

PMID: 16802356
DOI: 10.1002/art.21943

Genes

CCR7
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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