Article
Dysregulation of anergy-related factors involved in regulatory T cells defects in Systemic Lupus Erythematosus patients: Rapamycin and Vitamin D efficacy in restoring regulatory T cells.
International journal of rheumatic diseases - 1 Dec 2016
Banica Leontina M, Besliu Alina N, Pistol Gina C, Stavaru Crina, Vlad Violeta, Predeteanu Denisa, Ionescu Ruxandra, Stefanescu Maria, Matache Cristiana
Abstract excerpt
AIM: Systemic Lupus Erythematosus (SLE) patients display dysfunctions in T cell activation and anergy. Therefore the aims of our study were to explore the expression of anergy-related factors in CD4+ T cells in relationship with regulatory T cells (Tregs) frequency in SLE patients and to identify strategies to redress these defects. METHOD: Casitas B-cell lymphoma b (Cbl-b) and 'gene related to anergy in...
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