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Article

A polymorphism of the YTHDF2 gene (1p35) located in an Alu-rich genomic domain is associated with human longevity.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jun 2006

Cardelli Maurizio, Marchegiani Francesca, Cavallone Luca, Olivieri Fabiola, Giovagnetti Simona, Mugianesi Elena, Moresi Raffaella, Lisa Rosamaria, Franceschi Claudio

Abstract excerpt

The uneven distribution of Alu repetitive elements in the human genome is related to specific functional properties of genomic regions. We report the identification of a locus associated with human longevity in one of the chromosomal regions with the highest density of Alu elements, in 1p35. The locus, corresponding to a (TG)n microsatellite in the YTHDF2 gene, was identified by characterizing an "anonymous"...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16799135
DOI: 10.1093/gerona/61.6.547

Genes

YTHDF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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