Article
A CX3CR1 genotype associated with retinal vasculitis in patients in the United Kingdom.
Investigative ophthalmology & visual science - 1 Jul 2006
Wallace Graham R, Vaughan Robert W, Kondeatis Elly, Mathew Rashmi, Chen Yuanneng, Graham Elizabeth M, Stanford Miles R
Abstract excerpt
PURPOSE: To investigate whether polymorphisms in the gene encoding the chemokine receptor CX3CR1, which has been linked to changes in functional ligand-binding activity, are associated with retinal vasculitis (RV) in a cohort of patients in the United Kingdom. METHODS: DNA was prepared from whole blood of 126 patients with RV and 95 healthy individuals by a standard salting-out procedure. Two polymorphisms, V249I...
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