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Article

Genetic study of the hepcidin gene (HAMP) promoter and functional analysis of the c.-582A > G variant.

BMC genetics - 10 Dec 2010

Parajes Silvia, González-Quintela Arturo, Campos Joaquín, Quinteiro Celsa, Domínguez Fernando, Loidi Lourdes

Abstract excerpt

BACKGROUND: Hepcidin acts as the main regulator of iron homeostasis through regulation of intestinal absorption and macrophage release. Hepcidin deficiency causes iron overload whereas its overproduction is associated with anaemia of chronic diseases. The aims of the study were: to identify genetic variants in the hepcidin gene (HAMP) promoter, to asses the associations between the variants found and iron status...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21143959
DOI: 10.1186/1471-2156-11-110
PMCID: PMC3004809

Genes

HAMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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