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Article

Characterization of human collagen XVIII promoter 2: interaction of Sp1, Sp3 and YY1 with the regulatory region and a SNP that increases transcription in hepatocytes.

Matrix biology : journal of the International Society for Matrix Biology - 1 Dec 2005

Armelin-Correa Lucia M, Lin Chin J, Barbosa Angela, Bagatini Kelly, Winnischofer Sheila M B, Sogayar Mari C, Passos-Bueno Maria Rita

Abstract excerpt

Different levels of Collagen XVIII expression have been associated with several pathological processes such as cancer, liver fibrosis, diabetic retinopathy and Alzheimer's disease. Understanding the transcriptional regulation of Collagen XVIII might elucidate some pathways related to the progression of these diseases. The promoter 2 of COL18A1 gene is poorly understood and is responsible for the transcription of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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PMID: 16229994
DOI: 10.1016/j.matbio.2005.08.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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