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Article

Study of Pax6 mutant rat revealed the association between upper incisor formation and midface formation.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2006

Kriangkrai Rungarun, Chareonvit Suconta, Yahagi Koichi, Fujiwara Michio, Eto Kazuhiro, Iseki Sachiko

Abstract excerpt

In this study, we investigated the process of supernumerary upper incisor formation in the Pax6 mutant rat, rSey(2)/rSey(2), which exhibits a facial cleft between the medial nasal and maxillary processes. Histological investigation and epithelial labeling studies of wild type rat embryos indicated that the upper incisor develops by fusion of two primary dental placodes (PDPs) in the medial nasal process with a...

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PMID: 16795023
DOI: 10.1002/dvdy.20875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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