Article
Preparation of cultured skin for transplantation using insulin-like growth factor I in conjunction with insulin-like growth factor binding protein 5, epidermal growth factor, and vitronectin.
Transplantation - 27 Jun 2006
Dawson Rebecca A, Upton Zee, Malda Jos, Harkin Damien G
Abstract excerpt
BACKGROUND: Cultured skin for transplantation is routinely prepared by growing patient keratinocytes in the presence of semidefined sources of growth factors including serum and feeder cells, but these materials require substantial risk remediation and can contribute to transplant rejection. METHODS: We have therefore investigated the potential of a novel combination of recombinant and purified growth factors to...
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