Article
Evaluation of a preclinical blood test for scrapie in sheep using immunocapillary electrophoresis.
Journal of AOAC International - 1 Jan 2000
Jackman Roy, Everest David J, Schmerr Mary Jo, Khawaja Mohammed, Keep Pat, Docherty John
Abstract excerpt
An analytical method is described for detection of endogenous disease-associated prion protein in the buffy coat fraction from the blood of sheep infected with scrapie. The method has been improved and evaluated for its performance in the preclinical diagnosis of ovine transmissible spongiform encephalopathies. The test system uses a protocol for sample preparation that includes extraction and concentration and a...
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