Nonrandom distribution of N-myc oncogene genotypes in neuroblastoma.

doi:10.1093/jnci/83.15.1085

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Article

Nonrandom distribution of N-myc oncogene genotypes in neuroblastoma.

Journal of the National Cancer Institute - 7 Aug 1991

Waber P G, Bowcock A M, Arencibia-Mireles O, Nisen P D

Abstract excerpt

The distributions of Pvu II and Sph I alleles of the N-myc oncogene (also known as MYCN) were studied in a series of normal individuals and pediatric patients with solid tumors. In the case of Pvu II, where the polymorphic site is located 3' of the gene, the frequencies of the allele were 0.27 (1...

Topics

Alleles
Child
DNA
Female
Genotype
Humans
Male
Neuroblastoma
Oncogenes
Pedigree
Polymorphism, Restriction Fragment Length
Proto-Oncogene Proteins c-myc

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