Article
EHD1 regulates cholesterol homeostasis and lipid droplet storage.
Biochemical and biophysical research communications - 8 Jun 2007
Naslavsky Naava, Rahajeng Juliati, Rapaport Debora, Horowitz Mia, Caplan Steve
Abstract excerpt
Endocytic transport is critical for the subcellular distribution of free cholesterol and the endocytic recycling compartment (ERC) is an important organelle that stores cholesterol and regulates its trafficking. The C-terminal EHD protein, EHD1, controls receptor recycling through the ERC and affects free cholesterol distribution in the cell. We utilized embryonic fibroblasts from EHD1 knockout mice...
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