Article
Localization of mammalian NAD(P)H steroid dehydrogenase-like protein on lipid droplets.
The Journal of biological chemistry - 19 Sept 2003
Ohashi Masato, Mizushima Noboru, Kabeya Yukiko, Yoshimori Tamotsu
Abstract excerpt
Mammalian enzymes in late cholesterol biosynthesis have been localized uniformly over the endoplasmic reticulum by enzymatic methods. We report here the first mammalian cholesterol biosynthetic enzyme unequivocally localized at the surface of intracellular lipid storage droplets. NAD(P)H steroid dehydrogenase-like protein (Nsdhl), a mammalian C-3 sterol dehydrogenase involved in the conversion of lanosterol into...
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