[Analysis of the mitochondrial mutations of articular chondrocyte in temporomandibular joint osteoarthrosis].

Abstract excerpt

OBJECTIVE: To explore the significance of mitochondrial DNA mutations of articular chondrocytes in the rat model of temporomandibular joint osteoarthrosis (TMJOA). METHODS: TMJOA models were created in left sides of TMJ of 15 SD rats by the partial resection of the articular disc. The experimental rats were killed 3 months after operation. After the chondrocytes culture, the entire mtDNA were amplified using 32...

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