Article
Mutations in mitochondrial DNA and approaches for their correction.
Biochemistry. Biokhimiia - 1 Nov 2014
Patrushev M V, Kamenski P A, Mazunin I O
Abstract excerpt
Apart from the nucleus, the mitochondrion is the only organelle of an animal cell that contains its own genome. Mitochondrial DNA is much less in size than the nuclear one and codes for only several dozens of biological macromolecules. Nevertheless, mutations in mitochondrial genes often result in the occurrence of serious hereditary neuromuscular diseases. New mitochondrial DNA mutations and their relations to...
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