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The combination of<i>SPP1</i>knockdown and gemcitabine treatment enhances apoptosis and reduces invasiveness of pancreatic cancer cells

2024-05-06

Abstract excerpt

<h4>Background</h4> Pancreatic ductal adenocarcinoma (PDAC) is poised to be a leading cause of cancer-related deaths. Despite developing new treatment strategies, patient outcomes have not significantly improved. Chemoresistance has been implicated as a major contributor to ineffective treatments observed with studies suggesting combination therapy targeting multiple pathways. This study explored dysregulated gene...

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Literature Corpus work
76217d40-b5b9-5eb0-a2f1-5313044f4546
DOI
10.1101/2024.05.05.24306611
Open publication

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