Ultrastructural evidence of intercalated disc remodelling in arrhythmogenic right ventricular cardiomyopathy: an electron microscopy investigation on endomyocardial biopsies.

doi:10.1093/eurheartj/ehl095

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Article

Ultrastructural evidence of intercalated disc remodelling in arrhythmogenic right ventricular cardiomyopathy: an electron microscopy investigation on endomyocardial biopsies.

European heart journal - 1 Aug 2006

Basso Cristina, Czarnowska Elzbieta, Della Barbera Mila, Bauce Barbara, Beffagna Giorgia, Wlodarska Elzbieta K, Pilichou Kalliopi, Ramondo Angelo, Lorenzon Alessandra, Wozniek Olgierd, Corrado Domenico, Daliento Luciano, Danieli Gian Antonio, Valente Marialuisa, Nava Andrea, Thiene Gaetano, Rampazzo Alessandra

Abstract excerpt

AIMS: The ultrastructural features of the myocardium in arrhythmogenic right ventricular cardiomyopathy (ARVC) have not been systematically investigated so far. The recent discovery of gene mutations encoding intercalated disc proteins prompted us to perform a transmission electron microscopy study on endomyocardial biopsies. METHODS AND RESULTS: Twenty-one ARVC probands who fulfilled the international Task Force...

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PMID: 16774985
DOI: 10.1093/eurheartj/ehl095

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