Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular composition of the intercalated disc in a spontaneous canine animal model of arrhythmogenic right ventricular dysplasia/cardiomyopathy.

Heart rhythm - 1 Sept 2007

Oxford Eva M, Everitt Melanie, Coombs Wanda, Fox Philip R, Kraus Marc, Gelzer Anna R M, Saffitz Jeffrey, Taffet Steven M, Moïse N Sydney, Delmar Mario

Abstract excerpt

BACKGROUND: Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is characterized by ventricular arrhythmias, sudden death, and fatty or fibrofatty replacement of right ventricular myocytes. Recent studies have noted an association between human ARVD/C and molecular remodeling of intercalated disc structures. However, progress has been constrained by limitations inherent to human studies. OBJECTIVE:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arrhythmogenic Right Ventricular Dysplasia
Share to Blotting, Western

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cadherins

Share to Connexin 43

Share to Cytoskeletal Proteins

Share to Gap Junctions

Share to Myocytes, Cardiac

Source

Open in PubMed Open full text

Identifiers

PMID: 17765621
DOI: 10.1016/j.hrthm.2007.05.025
PMCID: PMC2080779

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular composition of the intercalated disc in a spontaneous canine animal model of arrhythmogenic right ventricular dysplasia/cardiomyopathy.PMID 17765621Read ↗

Disturbed Desmoglein-2 in the intercalated disc of pediatric patients with dilated cardiomyopathy.Semantic proximity Read ↗

Remodeling of the cardiac sodium channel, connexin43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy.Semantic proximity Read ↗

Desmosomal Cadherins Are Decreased in Explanted Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patient HeartsSemantic proximity Read ↗

Ultrastructural changes in cardiac myocytes from Boxer dogs with arrhythmogenic right ventricular cardiomyopathySemantic proximity Read ↗

Animal models of arrhythmogenic right ventricular cardiomyopathy: what have we learned and where do we go? Insight for therapeutics.Semantic proximity Read ↗

Cardiac Tissue-Restricted Deletion of Plakoglobin Results in Progressive Cardiomyopathy and Activation of β-Catenin SignalingSemantic proximity Read ↗

Arrhythmogenic cardiomyopathy and abnormalities of cell-to-cell coupling.Semantic proximity Read ↗

Role of plakophilin-2 expression on exercise-related progression of arrhythmogenic right ventricular cardiomyopathy: a translational study.Semantic proximity Read ↗

A New Diagnostic Test for Arrhythmogenic Right Ventricular CardiomyopathySemantic proximity Read ↗

Ultrastructural evidence of intercalated disc remodelling in arrhythmogenic right ventricular cardiomyopathy: an electron microscopy investigation on endomyocardial biopsies.Semantic proximity Read ↗

Abnormal connexin43 in arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 mutations.Semantic proximity Read ↗

Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.