Article
Molecular biology and clinical management of arrhythmogenic right ventricular cardiomyopathy/dysplasia.
Heart (British Cardiac Society) - 1 Apr 2011
Corrado Domenico, Basso Cristina, Pilichou Kalliopi, Thiene Gaetano
Abstract excerpt
In the last two decades the extraordinary advances in molecular biology of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) have provided significant insights into our understanding of the disease aetiology by showing that it is a genetic disorder of the cardiac desmosomes and that interactions between mechanical disruption of cell-cell adhesion and defects of desmosomal-mediated intracellular...
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