Article
Goat SRY induces testis development in XX transgenic mice.
FEBS letters - 26 Jun 2006
Pannetier Maëlle, Tilly Gaëlle, Kocer Ayhan, Hudrisier Marthe, Renault Lauriane, Chesnais Nathalie, Costa José, Le Provost Fabienne, Vaiman Daniel, Vilotte Jean-Luc, Pailhoux Eric
Abstract excerpt
The testis-determining gene SRY is not well-conserved among mammals, particularly between mouse and other mammals, both in terms of protein structure and of expression regulation. To evaluate SRY phylogenic conservation in regards to its function, we expressed the goat gene (gSRY) in XX transgeni...
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