Article
MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants.
DNA repair - 13 Jul 2006
Foster Steven S, Zubko Mikhajlo K, Guillard Sandrine, Lydall David
Abstract excerpt
MRX, an evolutionally conserved DNA damage response complex composed of Mre11, Rad50 and Xrs2, is involved in DNA double strand break (DSB) repair, checkpoint activation and telomere maintenance. At DSBs, MRX plays a role in generating single stranded DNA (ssDNA) and signalling cell cycle arrest....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
