Article
Meta-analysis of association between the T102C polymorphism of the 5HT2a receptor gene and schizophrenia.
Schizophrenia research - 1 Mar 2004
Abdolmaleky Hamid Mostafavi, Faraone Stephen V, Glatt Stephen J, Tsuang Ming T
Abstract excerpt
A meta-analysis of whole-genome linkage scans confirmed linkage between schizophrenia and markers on the long arm of chromosome 13. The gene HTR2A, which codes for the 5HT2a receptor, is located in this area. The T102C single nucleotide polymorphism of HTR2A has been the subject of much research. The production of the C-allele form of HTR2A is significantly less than that of the T-allele form in normal controls...
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