Article
No association between T102C polymorphism of serotonin-2A receptor gene and clinical phenotypes of Chinese schizophrenic patients.
Psychiatry research - 31 Dec 2001
Chen R Y, Sham P, Chen E Y, Li T, Cheung E F, Hui T C, Kwok C L, Lieh-Mak F, Zhao J H, Collier D, Murray R
Abstract excerpt
Serotonin dysfunction has been implicated in the pathogenesis of schizophrenia. Previous studies have shown an association between the T102C polymorphism of the 5HT2a receptor gene and schizophrenia. However, negative findings have also been reported. One possible explanation for such discrepancy is disease heterogeneity due to the current limitations in the diagnosis of schizophrenia. We conducted a case-control...
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