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Article

Dioxygen activation at non-heme diiron centers: characterization of intermediates in a mutant form of toluene/o-xylene monooxygenase hydroxylase.

Journal of the American Chemical Society - 14 Jun 2006

Murray Leslie J, García-Serres Ricardo, Naik Sunil, Huynh Boi Hanh, Lippard Stephen J

Abstract excerpt

We report the generation and characterization of an intermediate in a mutant form of the toluene/o-xylene monooxygenase hydroxylase component from Pseudomonas stutzeri OX1. The reaction of chemically reduced I100W variant in the presence of the coupling protein, ToMOD, with dioxygen was monitored by stopped-flow UV/visible spectroscopy. Rapid-freeze quench (RFQ) samples were also generated for EPR and Mössbauer...

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Identifiers

PMID: 16756297
DOI: 10.1021/ja062762l
PMCID: PMC2501110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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