Article
[Polymorphism of gene promotor region for MMP-2 in rheumatoid arthritis].
Vnitrni lekarstvi - 1 Apr 2006
Nemec P, Goldbergová M, Swobodnik T, Polásková D, Soucek M, Vasků A
Abstract excerpt
INTRODUCTION: Matrix metalloproteinase (MMP) belonging to family of zinc-dependent endopeptidases participates in remodelling of extracellular matrix in many physiological and pathological processes including rheumatoid arthritis (RA). Rheumatoid arthritis is a chronic autoimmune inflammatory multi-systemic disease characterized, among others, by degradation of hyaline articular cartilage and escalated...
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