Article
Mutation of the atrophin2 gene in the zebrafish disrupts signaling by fibroblast growth factor during development of the inner ear.
Proceedings of the National Academy of Sciences of the United States of America - 13 Jun 2006
Asai Yukako, Chan Dylan K, Starr Catherine J, Kappler James A, Kollmar Richard, Hudspeth A J
Abstract excerpt
The development of the vertebrate inner ear depends on the precise expression of fibroblast growth factors. In a mutagenesis screen for zebrafish with abnormalities of inner-ear development and behavior, we isolated a mutant line, ru622, whose phenotypic characteristics resembled those of null mu...
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