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Article

Physiological Regulation of ATP Release at the Apical Surface of Human Airway Epithelia

5 Jun 2006

Abstract excerpt

Extracellular ATP and its metabolite adenosine regulate mucociliary clearance in airway epithelia. Little has been known, however, regarding the actual ATP and adenosine concentrations in the thin ( approximately 7 microm) liquid layer lining native airway surfaces and the link between ATP release/metabolism and autocrine/paracrine regulation of epithelial function. In this study, chimeric Staphylococcus aureus...

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PMID: 16754672
DOI: 10.1074/jbc.m603019200

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