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Article

Absence of allelic loss on chromosome 5q by RFLP analysis in preleukemia.

Leukemia research - 1 Jan 1991

Shepherd L, Cameron C, Galbraith P, Windsor S, Lillicrap D

Abstract excerpt

Thirty-eight patients with various forms of myelodysplastic syndrome (MDS) were studied for the loss of restriction fragment length polymorphism (RFLP) heterozygosity on chromosome 5q as inferential support for the presence of a growth regulatory locus in this area of the genome. Conventional chromosomal analysis was performed in addition to RFLP studies of constitutive and granulocyte DNA using five...

Topics

Alleles
Biopsy
Bone Marrow
Chromosome Aberrations
Chromosome Banding
Chromosome Deletion
Chromosome Disorders
Chromosomes, Human, Pair 5
DNA, Neoplasm
Humans
Myelodysplastic Syndromes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Preleukemia

Skin

Source

Identifiers

PMID: 1675299
DOI: 10.1016/0145-2126(91)90004-d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1675299-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Absence of allelic loss on chromosome 5q by RFLP analysis in preleukemia.PMID 1675299Read ↗

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Physical mapping of the minimal region of loss in 5q- chromosome.Semantic proximity Read ↗

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