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Article

Physical mapping of the minimal region of loss in 5q- chromosome.

Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1995

Fairman J, Chumakov I, Chinault A C, Nowell P C, Nagarajan L

Abstract excerpt

Acquired interstitial loss of all or part of the long arm of human chromosome 5 (5q-) is an anomaly that is seen frequently in patients with preleukemic myelodysplasia and acute myelogenous leukemia. Loss of a critical region of overlap at band 5q31.1 in all of these cases, with various cytogenetic breaks, signifies the existence of a key negative regulator of leukemogenesis. Previous studies have defined the...

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Source

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Identifiers

PMID: 7638206
DOI: 10.1073/pnas.92.16.7406
PMCID: PMC41348

Genes

EGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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