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Article

Stratification based on language-related endophenotypes in autism: attempt to replicate reported linkage.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2006

Spence Sarah J, Cantor Rita M, Chung Lien, Kim Sharon, Geschwind Daniel H, Alarcón Maricela

Abstract excerpt

The identification of autism susceptibility genes has been hampered by phenotypic heterogeneity of autism, among other factors. However, the use of endophenotypes has shown preliminary success in reducing heterogeneity and identifying potential autism-related susceptibility regions. To further explore the utility of using language-related endophenotypes, we performed linkage analysis on multiplex autism families...

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Identifiers

PMID: 16752361
DOI: 10.1002/ajmg.b.30329
PMCID: PMC3653581

Genes

NPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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