Article
Quantitative genome scan and Ordered-Subsets Analysis of autism endophenotypes support language QTLs.
Molecular psychiatry - 1 Aug 2005
Alarcón M, Yonan A L, Gilliam T C, Cantor R M, Geschwind D H
Abstract excerpt
Autism is a neurodevelopmental syndrome with early childhood onset and deficits in three behavioral and cognitive dimensions: language, social skills and repetitive or restrictive behaviors. We hypothesized that using these endophenotypes would provide more power to detect linkage than the diagnosis of autism. Previously, we reported results for a nonparametric quantitative trait locus (QTL) genome scan in 152...
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